Sep 4, 2010 vs. Washington
- Provo, UT at LaVell Edwards Stadium, WIN 23-17 - Channel CBS C-HD
Sep 11, 2010 vs. Air Force
- Air Force Academy, CO at Falcon Stadium, LOSS 14-35 - Channel Versus HD
Sep 18, 2010 vs Florida State
- Tallahassee, FL at Doak Campbell Stadium, LOSS 10-34 - Channel ESPNU BYUtv
Sep 25, 2010 vs. Nevada
- Provo, UT at LaVell Edwards Stadium, LOSS 13-27 - Channel The Mtn. HD
Oct 1, 2010 vs. Utah State
- Logan, UT at Romney Stadium, LOSS 16-31 - Channel ESPN HD BYUtv
Oct 9, 2010 vs. San Diego State (Homecoming)
- Provo, UT at LaVell Edwards Stadium, WIN 24-21 - Channel The Mtn. HD
Oct 16, 2010 vs. No. 4 TCU
- Forth Worth, TX at Amon G. Carter Stadium - LOSS 3-31 - Channel Versus HD
Oct 23, 2010 vs. Wyoming
- Provo, UT at LaVell Edwards Stadium - Win 25-20 - Channel - The Mtn. HD
Nov 6, 2010 vs. UNLV
- Provo, UT at LaVell Edwards Stadium - WIN 55-7 - Channel The Mtn. HD
Nov 13, 2010 vs Colorado State
- Fort Collins, CO at Hughes Stadium - WIN 49-10 - Channel The Mtn. HD
Nov 20, 2010 vs. New Mexico
- Provo, UT at LaVell Edwards Stadium - WIN 40-7 - Channel The Mtn. HD
Nov 27, 2010 vs. No. 22 Utah
- Salt Lake City, UT at Rice-Eccles Stadium - LOSS 16-17 - Channel CBS C-HD, The Mtn. HD
New Mexico Bowl[]
Dec 18, 2010 vs. UTEP
- Albuquerque, NM at University Stadium - WIN 52-24 - Channel ESPN HD, ESPN